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TERATEC Forum 2014
Workshop 7 - Wednesday, July 2, 2014

HPC and Healthcare: From therapeutic research to personalized medicine

Chaired by Etienne DE POMMERY et Claude CAMOZZI

The field of healthcare is no stranger to progress in modeling and computing technologies, although they are more common in other more industrial sectors of the economy. Thanks to the increased capacity of supercomputers, we are now able to model more physico-chemical and physiological phenomena, which will eventually allow us to provide increasingly personalized medical care. Combining imaging results with very high-performance simulation will lead to real-time diagnostic ability and valuable decision support while controlling operating risks and offering a choice in prosthetics design and fitting options.

In addition, understanding the way molecules act on the cells will allow for more targeted medications that generate fewer side effects, created initially via modeling—this will be particularly useful for rare diseases, cancer research, and combined conditions.

Digital simulation can also use its large computing capacity to rule out all but the optimal configurations for clinical trials, pre-testing them virtually like the virtual prototyping methods used in industry, where testing is carried out only to give the final stamp of approval to technical choices made upstream based on simulation.

Les simulations HPC pour le décryptage des interactions moléculaires et l’obtention de nouvelles cibles thérapeutiques
Manuel DAUCHEZ, Professeur de Biophysique et Biochimie Computationnelle, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE

Abstract & Biography

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Predictive and patient-specific numerical simulations of endovascular surgery for aortic abdominal aneurysms
Michel ROCHETTE, Director of Research, ANSYS

Abstract & Biography

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Application of Optimization & CFD in Surgical Planning for Percutaneous Coronary Intervention
Silvia POLES, Senior Application Engineer, NOESIS Solutions

Abstract & Biography

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Simulations for Abdominal Wall Reconstruction
Frédéric TURQUIER, PhD, Director Research & Development, COVIDIEN Surgical Solutions

Abstract & Biography

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Interpretation of Clinical Exome : Le Big Data comme brique d’assistance aux choix thérapeutiques en oncologie.
Philippe RAVIX Directeur Innovation SOGETI HIGH TECH

Abstract & Biography

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Le calcul haute performance pour l'analyse de données de neuroimagerie-génétique en grandes dimensions.
Benoit DA MOTA, Expert hpc&bioinformatics, ALLIANCE SERVICES PLUS - Edouard DUCHESNAY, research Engineer, NEUROSPIN

Abstract & Biography

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Biology and healthcare are beginning to rely more and more heavily on information and communication technologies, including high performance computing. Applications include processing large volumes of data or information (biological (genomic, proteomic) or clinical (medical imaging, epidemiology, etc.)) and simulating complex phenomena (molecular modeling, physiome, disease mechanisms, medication effects, design for nanosystems, biomaterials, artificial organs, surgical robots or robots to assist the disabled, etc.). All of the activities related to monitoring and assisting patients (smart systems, remote medicine, etc.) also benefit. As you can see, these technologies have applications in all medical needs related to prevention, diagnosis, and treatment.  After Dr. François Ballet, chairman of the R&D Committee for the MEDICEN competitiveness cluster, gave an introductory presentation reviewing the main current uses of HPC in healthcare, a point was made at two specific fields of application: Integrative biology, particularly in researching and designing new medications, The use of medical imaging and virtual reality techniques Through these presentations and the ensuing discussions, this workshop organized by TERATEC and MEDICEN aimed to lay a general foundation for future initiatives combining healthcare and HPC.

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